p21 anticorps

N° du produit ABIN1838031

Cet anticorps anti-p21 est un anticorps Souris Monoclonal détectant p21 dans WB, IHC, ELISA, FACS, IHC (p) et IHC (fro). Adapté pour Humain.

Aperçu rapide pour p21 anticorps (ABIN1838031)

Antigène: p21 (CDKN1A) (Cyclin-Dependent Kinase Inhibitor 1A (p21, Cip1) (CDKN1A))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp p21 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: WA-1

Détail du produit anti-p21 anticorps

Specificité: Clone WA-1 reacts with human and other mammalian p21 protein. The intracellular protein p21 is a 21 kD protein and also known as wild-type p53-activated fragment 1 (WAF1). It is an inhibitor of cyclin-dependent kinases (Cdks) and proliferating-cell nuclear antigen (PCNA). Source: A BALB/c mouse was immunized with human p21 protein. Splenocytes were fused with mouse myeloma cell line SP2. Hybridomas were selected in DMEM supplied with 20 % FCS, 1gg/mL azaserine and 10-4 M hypoxanthine. The immunoglobulin producing hybridoma with desired specificity was cloned twice by limiting dilution.

Purification: Purified

Immunogène: Human p21 protein. Splenocytes were fused with mouse myeloma cell line SP2. Hybridomas were selected in DMEM supplied with 20% FCS, 1 ug/ml azaserine and 10-4 M hypoxanthine. The immunoglobulin producing hybridoma with desired specificity was cloned twice by limiting dilution.

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

Target Species of Antibody: Human

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store at 4°C.

Détails sur p21

Antigène: p21 (CDKN1A) (Cyclin-Dependent Kinase Inhibitor 1A (p21, Cip1) (CDKN1A))

Autre désignation: CDKN1A / WAF1 / p21

Sujet: Name/Gene ID: CDKN1A

Synonyms: CDKN1A, CDKN1, CIP1, CDK-interacting protein 1, DNA synthesis inhibitor, p21CIP1, MDA6, PIC1, SDI1, WAF1, CAP20, CDK-interaction protein 1, MDA-6, p21

ID gène: 1026

UniProt: P38936

Pathways: Signalisation p53, Signalisation PI3K-Akt, Cycle Cellulaire, AMPK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Mitotic G1-G1/S Phases, DNA Replication, Hepatitis C, Synthesis of DNA, Autophagy