SMAD3 anticorps (pSer425)

N° du produit ABIN1842543

Détail du produit anti-SMAD3 anticorps

Antigène: SMAD3 (SMAD, Mothers Against DPP Homolog 3 (SMAD3))

Épitope: pSer425

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SMAD3 est non-conjugé

Application: Immunohistochemistry (IHC), Immunofluorescence (IF)

Specificité: Rabbit Anti-Smad3 Polyclonal Antibody detects endogenous levels of total Smad3 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized non-phosphopeptide derived from human Smad3 around pSer425 (C-S-S-V-SP).

Isotype: IgG

Information d'application

Indications d'application: IHC: 1:50-1:100,
IF: 1:100-1:200

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol

Agent conservateur: Sodium azide

Précaution d'utilisation: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Conseil sur la manipulation: Briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container's cap because small volumes of antibody will occasionally become entrapped in the seal of the product vial during shipment and storage.,
Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store at -20 °C for 1 year

Références pour anticorps anti-SMAD3 (ABIN1842543)

Tang, Yamashita, Coussens, Tang, Wang, Li, Deng, Cheng, Zhang: "Ablation of Smurf2 reveals an inhibition in TGF-? signalling through multiple mono-ubiquitination of Smad3." dans: The EMBO journal, Vol. 30, Issue 23, pp. 4777-89, (2011) (PubMed).

Détails sur SMAD3

Antigène: SMAD3 (SMAD, Mothers Against DPP Homolog 3 (SMAD3))

Autre désignation: Smad3 (SMAD3 Produits)

Synonymes: anticorps HSPC193, anticorps HsT17436, anticorps JV15-2, anticorps LDS1C, anticorps LDS3, anticorps MADH3, anticorps madh3, anticorps madh3a, anticorps smad3, anticorps wu:fa99e03, anticorps XSmad3, anticorps XenMLP, anticorps Xmad3, anticorps madh3-A, anticorps Madh3, anticorps AU022421, anticorps Smad 3, anticorps mad3, anticorps madh3b, anticorps zgc:92234, anticorps SMAD family member 3, anticorps SMAD family member 3a, anticorps SMAD family member 3 L homeolog, anticorps SMAD family member 3b, anticorps SMAD3, anticorps smad3a, anticorps smad3.L, anticorps Smad3, anticorps smad3b

Pathways: Cycle Cellulaire, Chromatin Binding, Cell-Cell Junction Organization, Positive Regulation of Endopeptidase Activity, Autophagy