LIG4 anticorps (N-Term)

N° du produit ABIN1881497

L’anticorps Lapin Polyclonal anti-LIG4 a été validé pour WB. Il convient pour détecter LIG4 dans des échantillons de Humain.

Aperçu rapide pour LIG4 anticorps (N-Term) (ABIN1881497)

Antigène: LIG4 (Ligase IV, DNA, ATP-Dependent (LIG4))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LIG4 est non-conjugé

Application: Western Blotting (WB)

Clone: RB40331

Détail du produit anti-LIG4 anticorps

Épitope: AA 239-267, N-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This LIG4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 239-267 amino acids from the N-terminal region of human LIG4.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Détails sur LIG4

Antigène: LIG4 (Ligase IV, DNA, ATP-Dependent (LIG4))

Autre désignation: LIG4

Sujet: Efficiently joins single-strand breaks in a double-stranded polydeoxynucleotide in an ATP-dependent reaction. Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. The LIG4-XRCC4 complex is responsible for the NHEJ ligation step, and XRCC4 enhances the joining activity of LIG4. Binding of the LIG4-XRCC4 complex to DNA ends is dependent on the assembly of the DNA-dependent protein kinase complex DNA-PK to these DNA ends.

Poids moléculaire: 103971

NCBI Accession: NP_001091738, NP_002303, NP_996820

UniProt: P49917

Pathways: Réparation de l'ADN, Production of Molecular Mediator of Immune Response