NR2E1 anticorps (AA 75-102)

N° du produit ABIN1881585

Détail du produit anti-NR2E1 anticorps

Antigène: NR2E1 (Nuclear Receptor Subfamily 2, Group E, Member 1 (NR2E1))

Épitope: AA 75-102

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NR2E1 est non-conjugé

Application: Western Blotting (WB)

Homologie: C, M, X

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This NR2E1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 75-102 amino acids from the Central region of human NR2E1.

Clone: RB41747

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-NR2E1 (ABIN1881585)

Liu, Wang, Belz, Bock, Takacs, Radlwimmer, Barbus, Reifenberger, Lichter, Schütz: "The nuclear receptor tailless induces long-term neural stem cell expansion and brain tumor initiation." dans: Genes & development, Vol. 24, Issue 7, pp. 683-95, (2010) (PubMed).

Iwahara, Hisahara, Hayashi, Horio: "Transcriptional activation of NAD+-dependent protein deacetylase SIRT1 by nuclear receptor TLX." dans: Biochemical and biophysical research communications, Vol. 386, Issue 4, pp. 671-5, (2009) (PubMed).

de Krom, Staal, Ophoff, Hendriks, Buitelaar, Franke, de Jonge, Bolton, Collier, Curran, van Engeland, van Ree: "A common variant in DRD3 receptor is associated with autism spectrum disorder." dans: Biological psychiatry, Vol. 65, Issue 7, pp. 625-30, (2009) (PubMed).

Yokoyama, Takezawa, Schüle, Kitagawa, Kato: "Transrepressive function of TLX requires the histone demethylase LSD1." dans: Molecular and cellular biology, Vol. 28, Issue 12, pp. 3995-4003, (2008) (PubMed).

Détails sur NR2E1

Antigène: NR2E1 (Nuclear Receptor Subfamily 2, Group E, Member 1 (NR2E1))

Autre désignation: NR2E1 (NR2E1 Produits)

Synonymes: anticorps NR2E1, anticorps TLL, anticorps TLX, anticorps XTLL, anticorps Mtl1, anticorps Mtll, anticorps Tlx, anticorps fierce, anticorps frc, anticorps tailless, anticorps fc30e03, anticorps fc39f12, anticorps wu:fc30e03, anticorps wu:fc39f12, anticorps zgc:100991, anticorps Xtll, anticorps nr2e1-A, anticorps tlx, anticorps nuclear receptor subfamily 2 group E member 1, anticorps nuclear receptor subfamily 2, group E, member 1, anticorps nuclear receptor subfamily 2 group E member 1 S homeolog, anticorps NR2E1, anticorps Nr2e1, anticorps nr2e1, anticorps nr2e1.S

Sujet: Orphan receptor that binds DNA as a monomer to hormone response elements (HRE) containing an extended core motif half-site sequence 5'-AAGGTCA-3' in which the 5' flanking nucleotides participate in determining receptor specificity. May be required for brain development. May be involved in the regulation of retinal development (By similarity).

Poids moléculaire: 42589

NCBI Accession: NP_003260

UniProt: Q9Y466

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Stem Cell Maintenance