NR2E1 anticorps (Internal Region)

N° du produit ABIN6263720

Détail du produit anti-NR2E1 anticorps

Antigène: NR2E1 (Nuclear Receptor Subfamily 2, Group E, Member 1 (NR2E1))

Épitope: Internal Region

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NR2E1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Specificité: NR2E1 Antibody detects endogenous levels of total NR2E1.

Homologie: Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human NR2E1, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-3000, IHC 1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur NR2E1

Antigène: NR2E1 (Nuclear Receptor Subfamily 2, Group E, Member 1 (NR2E1))

Autre désignation: NR2E1 (NR2E1 Produits)

Synonymes: anticorps NR2E1, anticorps TLL, anticorps TLX, anticorps XTLL, anticorps Mtl1, anticorps Mtll, anticorps Tlx, anticorps fierce, anticorps frc, anticorps tailless, anticorps fc30e03, anticorps fc39f12, anticorps wu:fc30e03, anticorps wu:fc39f12, anticorps zgc:100991, anticorps Xtll, anticorps nr2e1-A, anticorps tlx, anticorps nuclear receptor subfamily 2 group E member 1, anticorps nuclear receptor subfamily 2, group E, member 1, anticorps nuclear receptor subfamily 2 group E member 1 S homeolog, anticorps NR2E1, anticorps Nr2e1, anticorps nr2e1, anticorps nr2e1.S

Sujet:

Description: Orphan receptor that binds DNA as a monomer to hormone response elements (HRE) containing an extended core motif half-site sequence 5'-AAGGTCA-3' in which the 5' flanking nucleotides participate in determining receptor specificity (By similarity). May be required to pattern anterior brain differentiation. Involved in the regulation of retinal development and essential for vision. During retinogenesis, regulates PTEN-Cyclin D expression via binding to the promoter region of PTEN and suppressing its activity (By similarity). May be involved in retinoic acid receptor (RAR) regulation in retinal cells.

Gene: NR2E1

Poids moléculaire: 43 kDa

ID gène: 7101

UniProt: Q9Y466

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Stem Cell Maintenance