PSMD5 anticorps (C-Term)

N° du produit ABIN1881699

Détail du produit anti-PSMD5 anticorps

Antigène: PSMD5 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 5 (PSMD5))

Épitope: AA 428-457, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PSMD5 est non-conjugé

Application: Western Blotting (WB)

Homologie: B, M

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This PSMD5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 428-457 amino acids from the C-terminal region of human PSMD5.

Clone: RB40968

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-PSMD5 (ABIN1881699)

Roelofs, Park, Haas, Tian, McAllister, Huo, Lee, Zhang, Shi, Gygi, Finley: "Chaperone-mediated pathway of proteasome regulatory particle assembly." dans: Nature, Vol. 459, Issue 7248, pp. 861-5, (2009) (PubMed).

Kaneko, Hamazaki, Iemura, Sasaki, Furuyama, Natsume, Tanaka, Murata: "Assembly pathway of the Mammalian proteasome base subcomplex is mediated by multiple specific chaperones." dans: Cell, Vol. 137, Issue 5, pp. 914-25, (2009) (PubMed).

Listovsky, Oren, Yudkovsky, Mahbubani, Weiss, Lebendiker, Brandeis: "Mammalian Cdh1/Fzr mediates its own degradation." dans: The EMBO journal, Vol. 23, Issue 7, pp. 1619-26, (2004) (PubMed).

Détails sur PSMD5

Antigène: PSMD5 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 5 (PSMD5))

Autre désignation: PSMD5 (PSMD5 Produits)

Synonymes: anticorps S5B, anticorps 1500032A03Rik, anticorps AW475925, anticorps S5b, anticorps W91691, anticorps mKIAA0072, anticorps proteasome 26S subunit, non-ATPase 5, anticorps proteasome (prosome, macropain) 26S subunit, non-ATPase, 5, anticorps PSMD5, anticorps Psmd5

Sujet: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator base.

Poids moléculaire: 56196

NCBI Accession: NP_001257356, NP_005038

UniProt: Q16401

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway