This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogène
This SDCBP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human SDCBP.
SDCBP
Reactivité: Humain
WB, IF
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
WB: 1:1000
Restrictions
For Research Use only
Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C,-20 °C
Date de péremption
6 months
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Qian, Shi, Pang, Wu, Yu, Li, Wang, Zhou: "[Identification and expression of two new secretory proteins associated with prostate cancer]." dans: Yi chuan = Hereditas / Zhongguo yi chuan xue hui bian ji, Vol. 32, Issue 3, pp. 235-41, (2010) (PubMed).
Hwangbo, Kim, Lee, Lee: "Activation of the integrin effector kinase focal adhesion kinase in cancer cells is regulated by crosstalk between protein kinase Calpha and the PDZ adapter protein mda-9/Syntenin." dans: Cancer research, Vol. 70, Issue 4, pp. 1645-55, (2010) (PubMed).
Beekman, Verhagen, Geijsen, Coffer: "Regulation of myelopoiesis through syntenin-mediated modulation of IL-5 receptor output." dans: Blood, Vol. 114, Issue 18, pp. 3917-27, (2009) (PubMed).
Sira, Yoshida, Takeuchi, Kashiwayama, Futatani, Kanegane, Sasahara, Ito, Mizuguchi, Imanaka, Miyawaki: "A novel immunoregulatory protein in human colostrum, syntenin-1, for promoting the development of IgA-producing cells from cord blood B cells." dans: International immunology, Vol. 21, Issue 9, pp. 1013-23, (2009) (PubMed).
Antigène
SDCBP
(Syndecan Binding Protein (Syntenin) (SDCBP))
The protein encoded by this gene was initially identified as a molecule linking syndecan-mediated signaling to the cytoskeleton. The syntenin protein contains tandemly repeated PDZ domains that bind the cytoplasmic, C-terminal domains of a variety of transmembrane proteins. This protein may also affect cytoskeletal-membrane organization, cell adhesion, protein trafficking, and the activation of transcription factors. The protein is primarily localized to membrane-associated adherens junctions and focal adhesions but is also found at the endoplasmic reticulum and nucleus. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq].