This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogène
This POLR2J3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 1-25 amino acids from the N-terminal region of human POLR2J3.
Clone
RB45111
Isotype
Ig Fraction
Indications d'application
WB: 1:1000
Restrictions
For Research Use only
Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C,-20 °C
Date de péremption
6 months
Grandemange, Schaller, Yamano, Du Manoir, Shpakovski, Mattei, Kedinger, Vigneron: "A human RNA polymerase II subunit is encoded by a recently generated multigene family." dans: BMC molecular biology, Vol. 2, pp. 14, (2003) (PubMed).
Hillier, Fulton, Fulton, Graves, Pepin, Wagner-McPherson, Layman, Maas, Jaeger, Walker, Wylie, Sekhon, Becker, OLaughlin, Schaller, Fewell, Delehaunty, Miner, Nash, Cordes, Du, Sun, Edwards et al.: "The DNA sequence of human chromosome 7. ..." dans: Nature, Vol. 424, Issue 6945, pp. 157-64, (2003) (PubMed).
Antigène
POLR2J3
(Polymerase (RNA) II (DNA Directed) Polypeptide J3 (POLR2J3))
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB11 is part of the core element with the central large cleft (By similarity).