HDAC1 anticorps

N° du produit ABIN1882195

Détail du produit anti-HDAC1 anticorps

Antigène: HDAC1 (Histone Deacetylase 1 (HDAC1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp HDAC1 est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is prepared by Euglobin precipitation followed by dialysis against PBS.

Immunogène: Purified His-tagged HDAC1 protein was used to produced this monoclonal antibody.

Clone: 1061CT1-3-1

Isotype: IgM kappa

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-HDAC1 (ABIN1882195)

Huynh, Fischle, Verdin, Bardwell: "BCoR, a novel corepressor involved in BCL-6 repression." dans: Genes & development, Vol. 14, Issue 14, pp. 1810-23, (2000) (PubMed).

Sparrow, Miska, Langley, Reynaud-Deonauth, Kotecha, Towers, Spohr, Kouzarides, Mohun: "MEF-2 function is modified by a novel co-repressor, MITR." dans: The EMBO journal, Vol. 18, Issue 18, pp. 5085-98, (1999) (PubMed).

Furukawa, Kawakami, Sudo, Inazawa, Matsumine, Akiyama, Nakamura: "Isolation and mapping of a human gene (RPD3L1) that is homologous to RPD3, a transcription factor in Saccharomyces cerevisiae." dans: Cytogenetics and cell genetics, Vol. 73, Issue 1-2, pp. 130-3, (1996) (PubMed).

Détails sur HDAC1

Antigène: HDAC1 (Histone Deacetylase 1 (HDAC1))

Autre désignation: HDAC1 (HDAC1 Produits)

Synonymes: anticorps GON-10, anticorps HD1, anticorps RPD3, anticorps RPD3L1, anticorps CG7471, anticorps DHDAC1, anticorps DRpd3, anticorps DmHDAC1, anticorps Dmel\\CG7471, anticorps E(var)3-64BC, anticorps HDAC, anticorps HDAC-1, anticorps HDAC1, anticorps Hdac1, anticorps Rpd3/HDAC, anticorps Su(var)3-26, anticorps Su(var)326, anticorps Su(var)328, anticorps dHDAC-1, anticorps dHDAC1, anticorps dRPD3, anticorps dRpd3, anticorps dmHDA401, anticorps drpd3, anticorps hdac1, anticorps l(3)04556, anticorps l(3)64Cc, anticorps rpd3, anticorps rpd[3], anticorps gon-10, anticorps hdac1b, anticorps rpd3l1, anticorps Rpd3, anticorps GB14706, anticorps hdac1-b, anticorps chunp6919, anticorps hdac-1, anticorps mp:zf637-2-001987, anticorps wu:fb19h11, anticorps wu:fi06f03, anticorps zgc:101582, anticorps zgc:65818, anticorps Hdac1-ps, anticorps MommeD5, anticorps ARABIDOPSIS HISTONE DEACETYLASE 1, anticorps ARABIDOPSIS HISTONE DEACETYLASE 19, anticorps ATHD1, anticorps ATHDA19, anticorps ATRPD3A, anticorps F20D10.250, anticorps F20D10_250, anticorps HDA1, anticorps HDA19, anticorps HISTONE DEACETYLASE, anticorps HISTONE DEACETYLASE 19, anticorps HISTONE DEACETYLASE19, anticorps RPD3A, anticorps histone deacetylase 1, anticorps HDM, anticorps ab21, anticorps hdac1a, anticorps histone deacetylase 1, anticorps Histone deacetylase 1, anticorps histone deacetylase, anticorps histone deacetylase 1 S homeolog, anticorps histone deacetylase Rpd3, anticorps histone deacetylase 1 L homeolog, anticorps HDAC1, anticorps hdac1.S, anticorps LOC411503, anticorps hdac1, anticorps Hdac1, anticorps HD1, anticorps hda-1, anticorps hdac1.L, anticorps LOC748850

Sujet: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Deacetylates SP proteins, SP1 and SP3, and regulates their function. Component of the BRG1-RB1-HDAC1 complex, which negatively regulates the CREST-mediated transcription in resting neurons. Upon calcium stimulation, HDAC1 is released from the complex and CREBBP is recruited, which facilitates transcriptional activation. Deacetylates TSHZ3 and regulates its transcriptional repressor activity. Deacetylates 'Lys-310' in RELA and thereby inhibits the transcriptional activity of NF-kappa-B. Component a RCOR/GFI/KDM1A/HDAC complex that suppresses, via histone deacetylase (HDAC) recruitment, a number of genes implicated in multilineage blood cell development.

Poids moléculaire: 55103

NCBI Accession: NP_004955

UniProt: Q13547

Pathways: Neurotrophin Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Mitotic G1-G1/S Phases, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Negative Regulation of intrinsic apoptotic Signaling, Embryonic Body Morphogenesis