RASSF1 anticorps (AA 50-334)

N° du produit ABIN1886518

Cet anticorps Lapin Polyclonal détecte spécifiquement RASSF1 dans WB et IF. Il présente une réactivité envers Humain.

Aperçu rapide pour RASSF1 anticorps (AA 50-334) (ABIN1886518)

Antigène: RASSF1 (Ras Association (RalGDS/AF-6) Domain Family Member 1 (RASSF1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RASSF1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Détail du produit anti-RASSF1 anticorps

Épitope: AA 50-334

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 50 and 334 of RASSF1

Information d'application

Indications d'application: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunofluorescence: 1.100-1.200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: Biohazard Informations: This product contains thimerosal which is hazardous.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Détails sur RASSF1

Antigène: RASSF1 (Ras Association (RalGDS/AF-6) Domain Family Member 1 (RASSF1))

Autre désignation: RASSF1

Sujet: This gene encodes a protein similar to the RAS effector proteins.Loss or altered expression of this gene has been associated with the pathogenesis of a variety of cancers, which suggests the tumor suppressor function of this gene.The inactivation of this gene was found to be correlated with the hypermethylation of its CpG-island promoter region.The encoded protein was found to interact with DNA repair protein XPA.The protein was also shown to inhibit the accumulation of cyclin D1, and thus induce cell cycle arrest.Seven alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.[provided by RefSeq]

Poids moléculaire: 39 kDa

ID gène: 11186

NCBI Accession: NP_733832, NM_170714