Renin in Preproprotein (AA 70-302) anticorps

N° du produit ABIN1886627

Détail du produit

Antigène: Renin in Preproprotein

Épitope: AA 70-302

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 70 and 302 of Human REN

Information d'application

Indications d'application: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.100-1.250

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: Biohazard Informations: This product contains thimerosal which is hazardous.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Détail du antigène

Antigène: Renin in Preproprotein

Sujet: Renin catalyzes the first step in the activation pathway of angiotensinogen--a cascade that can result in aldosterone release,vasoconstriction, and increase in blood pressure.Renin, an aspartyl protease, cleaves angiotensinogen to form angiotensin I, which is converted to angiotensin II by angiotensin I converting enzyme, an important regulator of blood pressure and electrolyte balance.Transcript variants that encode different protein isoforms and that arise from alternative splicing and the use of alternative promoters have been described, but their full-length nature has not been determined.Mutations in this gene have been shown to cause familial hyperproreninemia.[provided by RefSeq]
Synonyms: FLJ10761

Poids moléculaire: 45 kDa

ID gène: 5972

NCBI Accession: NP_000528, NM_000537