RHOA anticorps (AA 101-150)

N° du produit ABIN1886746

Cet anticorps Lapin Polyclonal détecte spécifiquement RHOA dans WB et IHC. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour RHOA anticorps (AA 101-150) (ABIN1886746)

Antigène: RHOA (Ras Homolog Gene Family, Member A (RHOA))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RHOA est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-RHOA anticorps

Épitope: AA 101-150

Immunogène: KLH conjugated synthetic peptide derived from human RhoA (101-150aa)

Information d'application

Indications d'application: Suggested dilutions:
Western blotting: 1.100-1.500

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 0.01 M PBS, pH 7.4 with 10 mg/ml BSA and 0.1 % Sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Stock: -20 °C

Stockage commentaire: Store at -20 °C/1 year

Date de péremption: 12 months

Détails sur RHOA

Antigène: RHOA (Ras Homolog Gene Family, Member A (RHOA))

Autre désignation: RhoA

Sujet: This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades.Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility.The protein encoded by this gene is prenylated at its C-terminus, and localizes to the cytoplasm and plasma membrane.It is thought to be important in cell locomotion.Overexpression of this gene is associated with tumor cell proliferation and metastasis.Multiple alternatively spliced variants, encoding the same protein, have been identified.References: Graham D.L.et al.Chem.Biol.9:375-381(2002) Snyder J.T.et al.Nat.Struct.Biol.9:468-475(2002) Longenecker K.et al.Acta Crystallogr.D 59:876-880(2003)
Synonyms: RhoA protein, Aplysia ras related homolog 12, ARH 12, ARH12

Poids moléculaire: 21 kDa

UniProt: P61586

Pathways: Dynamique des Microtubules, Signalisation WNT, Neurotrophin Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Actin Filament Polymerization, Cell-Cell Junction Organization, Positive Regulation of Endopeptidase Activity, Signaling Events mediated by VEGFR1 and VEGFR2, Thromboxane A2 Receptor Signaling, SARS-CoV-2 Protein Interactome