DHX58 anticorps (C-Term)

N° du produit ABIN1886910

Détail du produit anti-DHX58 anticorps

Antigène: DHX58 (DEXH (Asp-Glu-X-His) Box Polypeptide 58 (DHX58))

Épitope: C-Term

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DHX58 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Affinity chromatography purified via peptide column

Immunogène: 12 amino acid peptide from near the carboxy terminus of human LGP2.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Conseil sur la manipulation: Avoid freezing and thawing repeatly.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Détails sur DHX58

Antigène: DHX58 (DEXH (Asp-Glu-X-His) Box Polypeptide 58 (DHX58))

Autre désignation: LGP2 (DHX58 Produits)

Synonymes: anticorps MGC82787, anticorps DHX58, anticorps lgp2, anticorps D11LGP2, anticorps D11lgp2e, anticorps LGP2, anticorps RLR-3, anticorps B430001I08Rik, anticorps D11Lgp2e, anticorps LPG2, anticorps Lgp2, anticorps RGD1310093, anticorps DEXH-box helicase 58 L homeolog, anticorps DExH-box helicase 58, anticorps probable ATP-dependent RNA helicase DHX58, anticorps DEXH (Asp-Glu-X-His) box polypeptide 58, anticorps DEXH-box helicase 58, anticorps dhx58.L, anticorps DHX58, anticorps dhx58, anticorps LOC100566102, anticorps Dhx58

Sujet: Anti-viral innate immune responses are triggered by pathogen-associated molecular patters (such as the accumulation of intracellular nucleic acids resulting from virus infections) and represent the first line of defense against numerous infectious organisms.The Toll-like receptors (TLR) 3, 7, 8, and 9 are expressed in immune cells and function as transmembrane pattern recognition receptors to detect foreign nucleic acids.Other proteins that play similar roles, such as RIG-1 and MDA5 are members of a CARD-helicase family and are expressed in the cytoplasm.A third protein, LGP2, is similar to RIG-1 and MDA5, except for lacking a homologous CARD domain.It is thought to act as an element of negative-feedback regulation of intracellular antiviral signaling.At least four isoforms of LGP2 are known to exist.
Synonyms: DHX58, likely ortholog of mouse D11lgp2