SLITRK3
Reactivité: Humain
WB, IF (cc), IF (p)
Hôte: Lapin
Polyclonal
Alexa Fluor 488
Restrictions
For Research Use only
Format
Liquid
Buffer
PBS containing 0.02 % sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Conseil sur la manipulation
Avoid freezing and thawing repeatly.
Stock
4 °C/-20 °C
Stockage commentaire
Store at 4 °C for short term use.Store at -20 °C for long term preservation.
Antigène
SLITRK3
(SLIT and NTRK-Like Family, Member 3 (SLITRK3))
anticorps SLIT and NTRK-like family, member 3, anticorps SLIT and NTRK like family member 3, anticorps SKI like proto-oncogene, anticorps Slitrk3, anticorps SLITRK3, anticorps slitrk3, anticorps SKIL
Sujet
SLIT and NTRK-like family 3 (Slitrk3) is a member a protein family consisting of six homologous transmembrane proteins (Slitrk1-6) that share two conserved leucine-rich repeat domains in the extracellular domain and have significant homology to Slit, a secreted axonal growth-controlling protein.These proteins are also homologous to trk neurotrophin receptors in their intracellular domains.Expression of Slitrk proteins is highly restricted to neural and brain tumor tissues, but varies within the protein family.Like every other Slitrk protein except Slitrk1, overexpression of Slitrk3 inhibited neurite outgrowth in cultured neurons, suggesting that these proteins are involved in the control of neurite outgrowth. Synonyms: SLIT and NTRK-like family 3