AP3M1
Reactivité: Humain
WB, ELISA
Hôte: Lapin
Polyclonal
Biotin
Restrictions
For Research Use only
Format
Liquid
Buffer
PBS containing 0.02 % sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Conseil sur la manipulation
Avoid freezing and thawing repeatly.
Stock
4 °C/-20 °C
Stockage commentaire
Store at 4 °C for short term use.Store at -20 °C for long term preservation.
Antigène
AP3M1
(Adaptor-Related Protein Complex 3, mu 1 Subunit (AP3M1))
anticorps 1200013D09Rik, anticorps C78982, anticorps R75378, anticorps P47a, anticorps adaptor related protein complex 3 mu 1 subunit, anticorps adaptor-related protein complex 3, mu 1 subunit, anticorps AP3M1, anticorps Ap3m1
Sujet
The AP3 complex is a heterotetramer composed of two large adaptins (AP3D1, AP3B1 or AP3B2), a medium adaptin (AP3M1 or AP3M2) and a small adaptin (APS1 or AP3S2).The complex is associated with the Golgi region as well as more peripheral structures.It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes.AP3M1 is highly homologous to AP3M2 but is the preferred binding partner to the YQRL motif from the cytosolic domain of TGN38.AP3M1 has also been shown to interact with the HIV-1 virulence protein Nef. Synonyms: Adaptor-related protein complex 3 mu-1 subunit, AP-3 complex subunit mu-1, mu3A