RASD2 anticorps (C-Term)

N° du produit ABIN1887081

Détail du produit anti-RASD2 anticorps

Antigène: RASD2 (RASD Family, Member 2 (RASD2))

Épitope: C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RASD2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Purification: Affinity chromatography purified via peptide column

Immunogène: 15 amino acid peptide near the carboxy terminus of the human TEM2.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Conseil sur la manipulation: Avoid freezing and thawing repeatly.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Détails sur RASD2

Antigène: RASD2 (RASD Family, Member 2 (RASD2))

Autre désignation: TEM2 (RASD2 Produits)

Synonymes: anticorps RASD2, anticorps MGC:4834, anticorps Rhes, anticorps TEM2, anticorps 4930526B11Rik, anticorps AU045414, anticorps TEM-2, anticorps RASD family member 2, anticorps RASD family, member 2, anticorps RASD2, anticorps Rasd2

Sujet: Rhes, also known as tumor endothelial marker 2 (TEM2), is a small GTP-binding protein that is predominantly expressed in the striatal region of the brain.This protein belongs to the RASD subfamily of Ras-related GTP-binding protein superfamily and is thought to play a role in the normal development and function of the brain as mice lacking this gene showed increased anxiety levels and motor coordination deficits.Rhes was identified as TEM2 through analysis of genes whose expression was upregulated in tumor endothelium.Tumor endothelial markers are significantly up-regulated during angiogenesis and neoangiogenesis that are crucial for the growth of solid tumors.TEMs localized on the cell surface and conserved across species are of particular interest for future development of anti-angiogenic therapies.
Synonyms: Tumor endothelial marker 2, Ras homolog enriched in striatum, Rhes, RASD2

UniProt: Q96D21