SLITRK1 anticorps (C-Term)

N° du produit ABIN1887118

Détail du produit anti-SLITRK1 anticorps

Antigène: SLITRK1 (SLIT and NTRK-Like Family, Member 1 (SLITRK1))

Épitope: C-Term

Reactivité: Rat, Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SLITRK1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Réactivité croisée (Details): This antibody is predicted to have no cross-reactivity to other Slitrk proteins.

Purification: Affinity chromatography purified via peptide column

Immunogène: 16 amino acid peptide from near the carboxy terminus of human Slitrk1.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Conseil sur la manipulation: Avoid freezing and thawing repeatly.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Détails sur SLITRK1

Antigène: SLITRK1 (SLIT and NTRK-Like Family, Member 1 (SLITRK1))

Autre désignation: Slitrk1 (SLITRK1 Produits)

Synonymes: anticorps DKFZp459G0529, anticorps LRRC12, anticorps TTM, anticorps 3200001I04Rik, anticorps SLIT and NTRK like family member 1, anticorps SLIT and NTRK-like family, member 1, anticorps SLITRK1, anticorps slitrk1, anticorps Slitrk1

Sujet: SLIT and NTRK-like family 1 (Slitrk1) is a member a protein family consisting of six homologous transmembrane proteins (Slitrk1-6) that share two conserved leucine-rich repeat domains in the extracellular domain and have significant homology to Slit, a secreted axonal growth-controlling protein.These proteins are also homologous to trk neurotrophin receptors in their intracellular domains.Expression of Slitrk proteins is highly restricted to neural and brain tumor tissues, but varies within the family.For example, Slitrk1 is expressed primarily in mature neurons.Overexpression of Slitrk1 in transfected neuronal cells induced unipolar neurites, while expression of the other Slitrk proteins inhibited neurite outgrowth, suggesting that these proteins are involved in the control of neurite outgrowth.While Slitrk1 variants have been suggested associated with Tourette's Syndrome, it is thought to play only a minor role if at all.
Synonyms: SLIT and NTRK-like family 1

NCBI Accession: NP_443142