CLIP1 anticorps (C-Term)

N° du produit ABIN1887163

Détail du produit anti-CLIP1 anticorps

Antigène: CLIP1 (CAP-GLY Domain Containing Linker Protein 1 (CLIP1))

Épitope: C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CLIP1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Purification: Affinity chromatography purified via peptide column

Immunogène: 17 amino acid peptide from near the carboxy terminus of human CLIP170.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Conseil sur la manipulation: Avoid freezing and thawing repeatly.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Détails sur CLIP1

Antigène: CLIP1 (CAP-GLY Domain Containing Linker Protein 1 (CLIP1))

Autre désignation: CLIP170 (CLIP1 Produits)

Synonymes: anticorps RSN, anticorps CLIP1, anticorps clip170, anticorps clip-170, anticorps CLIP, anticorps CLIP-170, anticorps CLIP170, anticorps CYLN1, anticorps 1110007I12Rik, anticorps 4631429H07Rik, anticorps AV017631, anticorps C81039, anticorps Clip50, anticorps Rsn, anticorps mKIAA4046, anticorps restin, anticorps CAP-Gly domain containing linker protein 1, anticorps CAP-Gly domain-containing linker protein 1, anticorps CAP-Gly domain containing linker protein 1 L homeolog, anticorps CAP-GLY domain containing linker protein 1b, anticorps CAP-GLY domain containing linker protein 1, anticorps CLIP1, anticorps LOC100075022, anticorps clip1, anticorps clip1.L, anticorps clip1b, anticorps Clip1

Sujet: CLIP170 was initially identified as a new type of intermediate filament associated protein that is highly expressed in Reed-Sternberg cells, the tumoral cells diagnostic for Hodgkin's disease.Later experiments showed that it is located at microtubule plus ends and is required for the binding of endocytic carrier vesicles.CLIP170 has also been suggested to act with LIS1, a protein implicated in brain development, to regulate dynein/dynactin binding microtubules.Other studies suggest that CLIP170 can influence the formation of lamellipodia and cell invasion by invasive breast cancer cells by regulating the release of kinesin and IQGAP1 from a complex of those proteins, CLIP170 and Rac1.At least two isoforms of CLIP170 are known to exist.
Synonyms: CAP-Gly domain-containing linker protein 1, CLIP, CYLN1, Restin, RSN

NCBI Accession: NP_002947

Pathways: Dynamique des Microtubules