ESRP2 anticorps (C-Term)

N° du produit ABIN1887203

Détail du produit anti-ESRP2 anticorps

Antigène: ESRP2 (Epithelial Splicing Regulatory Protein 2 (ESRP2))

Épitope: C-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ESRP2 est non-conjugé

Application: Western Blotting (WB), ELISA

Réactivité croisée (Details): RBM35B antibody is predicted to not cross-react with other RBM35/ESRP family members. At least three isoforms of RBM35B are known to exist, this antibody will detect all three.

Purification: Affinity chromatography purified via peptide column

Immunogène: 17 amino acid peptide near the carboxy terminus of human RBM35B.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Conseil sur la manipulation: Avoid freezing and thawing repeatly.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Détails sur ESRP2

Antigène: ESRP2 (Epithelial Splicing Regulatory Protein 2 (ESRP2))

Autre désignation: RBM35B (ESRP2 Produits)

Synonymes: anticorps RBM35B, anticorps 9530027K23Rik, anticorps Rbm35b, anticorps RGD1310855, anticorps cb404, anticorps fa07a06, anticorps rbm35b, anticorps sb:cb404, anticorps zgc:77254, anticorps epithelial splicing regulatory protein 2, anticorps microRNA 6773, anticorps ESRP2, anticorps Esrp2, anticorps MIR6773, anticorps esrp2

Sujet: RBM35A, also known as ESRP2, is a mRNA splicing factor that with its related protein RBM35A (ESRP1) are coordinators of an epithelial cell-type-specific splicing program.Both RBM35B and RBM35A are involved in posttranscriptional regulation of a number of genes such as FGFR2, CD44, CTNND1, and ENAH by exerting a differential effect on protein translation via 5' UTRs of mRNAs, suggesting that these proteins are global regulators of an epithelial regulatory network.Loss of this global ESRP-regulated epithelial splicing programme induces the phenotypic changes in cell morphology that are observed during the epithelial-mesenchymal transition.
Synonyms: RNA-binding motif protein 35B, RMB35B, Epithelial splicing regulatory protein 2, ESRP2

NCBI Accession: NP_079215