LASS5 anticorps (C-Term)

N° du produit ABIN1887230

Détail du produit anti-LASS5 anticorps

Antigène: LASS5 (LAG1 Homolog, Ceramide Synthase 5 (LASS5))

Épitope: C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LASS5 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF)

Réactivité croisée (Details): Multiple isoforms of LASS5 are known to exist. This antibody may cross-react with the highly homologous LASS6.

Purification: Affinity chromatography purified via peptide column

Immunogène: 17 amino acid peptide near the carboxy terminus of the human LASS5.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Conseil sur la manipulation: Avoid freezing and thawing repeatly.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Détails sur LASS5

Antigène: LASS5 (LAG1 Homolog, Ceramide Synthase 5 (LASS5))

Autre désignation: LASS5 (LASS5 Produits)

Synonymes: anticorps lass5, anticorps trh4, anticorps LASS5, anticorps Trh4, anticorps 2310081H14Rik, anticorps AU045339, anticorps AW544927, anticorps Lass5, anticorps ceramide synthase 5, anticorps ceramide synthase 5 S homeolog, anticorps CERS5, anticorps cers5, anticorps cers5.S, anticorps Cers5

Sujet: The LASS (longevity assurance homolog) family members represent a subgroup of the homeobox gene family and are highly conserved from yeasts to mammals.Six members of this family of proteins have been characterized (LASS1-6) and all are involved in ceramide synthesis during cell growth regulation and cancer differentiation.LASS5, also called Trh4, is a 392 amino acid endoplasmic reticulum, multi-pass membrane protein.Functioning as a dihydro-ceramide synthase, LASS5 is involved in the production of sphingolipids containing mainly one fatty acid donor (N-linked palmitoyl-ceramide) in a fumonisin B1-independent manner.It uses palmitoyl-CoA as an acyl donor and is involved in the synthesis of C14, C16 and C18-ceramide.LASS5 is the most abundantly expressed and predominant ceramide synthase isoform in lung epithelia.Recent studies show that LASS5 partially correct growth and apoptosis.
Synonyms: Longevity Assurance Homolog 5, LAG1, TRH4

NCBI Accession: NP_671723