TMEM59L anticorps (C-Term)

N° du produit ABIN1887271

Détail du produit anti-TMEM59L anticorps

Antigène: TMEM59L (Transmembrane Protein 59-Like (TMEM59L))

Épitope: C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TMEM59L est non-conjugé

Application: Western Blotting (WB), ELISA

Réactivité croisée (Details): Multiple isoforms of TMEM59L are known to exist. TMEM59L antibody is predicted to not cross-react TMEM59.

Purification: Affinity chromatography purified via peptide column

Immunogène: 19 amino acid peptide near carboxy terminus of human TMEM59L.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Conseil sur la manipulation: Avoid freezing and thawing repeatly.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Détails sur TMEM59L

Antigène: TMEM59L (Transmembrane Protein 59-Like (TMEM59L))

Autre désignation: TMEM59L (TMEM59L Produits)

Synonymes: anticorps LOC719572, anticorps BSMAP, anticorps C19orf4, anticorps 5330410G16Rik, anticorps RGD1305557, anticorps transmembrane protein 59 like, anticorps transmembrane protein 59-like, anticorps TMEM59L, anticorps Tmem59l

Sujet: Processing of the amyloid precursor protein (APP) by two different proteases, called alpha- and beta-secretase, is a central regulatory event in the generation of the amyloid beta peptide (Abeta), which has a key role in Alzheimer disease (AD) pathogenesis.TMEM59L is a type I membrane glycoprotein that is expressed in the brain.A related protein, TMEM59, is a Golgi-localized protein that modulates the O-glycosylation and complex N-glycosylation steps occurring during the Golgi maturation of several proteins such as APP, BACE1, SEAP or PRNP and inhibits APP transport and shedding.
Synonyms: Transmembrane protein 59L, brain-specific membrane-anchored protein, BSMAP

NCBI Accession: NP_036241