PPPDE1 anticorps (C-Term)

N° du produit ABIN1887281

Détail du produit anti-PPPDE1 anticorps

Antigène: PPPDE1 (PPPDE Peptidase Domain Containing 1 (PPPDE1))

Épitope: C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PPPDE1 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Affinity chromatography purified via peptide column

Immunogène: 19 amino acid peptide near the carboxy terminus of human PNAS4.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Conseil sur la manipulation: Avoid freezing and thawing repeatly.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Détails sur PPPDE1

Antigène: PPPDE1 (PPPDE Peptidase Domain Containing 1 (PPPDE1))

Autre désignation: PNAS4 (PPPDE1 Produits)

Synonymes: anticorps PPPDE1, anticorps FAM152A, anticorps 5830417C01Rik, anticorps DeSI-2, anticorps Fam152a, anticorps Pppde1, anticorps DKFZp459O172, anticorps C1orf121, anticorps DESI, anticorps DESI1, anticorps PNAS-4, anticorps CGI-146, anticorps fam152a, anticorps pnas4, anticorps pppde1, anticorps cb238, anticorps desi1, anticorps sb:cb238, anticorps wu:fi12d12, anticorps zgc:100860, anticorps desumoylating isopeptidase 2, anticorps desumoylating isopeptidase 2 L homeolog, anticorps DESI2, anticorps Desi2, anticorps desi2.L, anticorps desi2

Sujet: PNAS4 is a highly conserved protein that shares high homology from plants to animals.It was initially identified as a putative apoptosis-related protein in the human acute promyelocytic leukemia cell line NB4.PNAS4 is activated during the early response to DNA damage and can inhibit proliferation via apoptosis when overexpressed in some tumor cells such as U2OS, SKOV3, and A549.PNAS4 inhibits tumor cell proliferation through the following mechanisms: (i) overexpression of PNAS4 causes S phase arrest by regulating the expression of cell cycle-related proteins and (ii) PNAS4 induces apoptosis through the mitochondrial apoptosis pathway.Recent evidence has shown that PNAS4 may be involved in the genesis of some cancers and could be a potential candidate for lung cancer therapy alone or in combination with gemcitabine.At least two isoforms of PNAS4 are known to exist.
Synonyms: PPPDE peptidase domain containing 1, CGI-146, FAM152A

NCBI Accession: NP_057160