TYW1 anticorps (C-Term)

N° du produit ABIN1887290

Détail du produit anti-TYW1 anticorps

Antigène: TYW1 (tRNA-YW Synthesizing Protein 1 Homolog (TYW1))

Épitope: C-Term

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TYW1 est non-conjugé

Application: Western Blotting (WB), ELISA

Réactivité croisée (Details): TYW1 antibody is predicted to not cross-react with other TYW protein family members. At least three isoforms of TYW1 are known to exist, this antibody will only detect the two larger isoforms.

Purification: Affinity chromatography purified via peptide column

Immunogène: 19 amino acid peptide near the carboxy terminus of human TYW1.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Conseil sur la manipulation: Avoid freezing and thawing repeatly.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Détails sur TYW1

Antigène: TYW1 (tRNA-YW Synthesizing Protein 1 Homolog (TYW1))

Autre désignation: TYW1 (TYW1 Produits)

Synonymes: anticorps RSAFD1, anticorps TYW1A, anticorps YPL207W, anticorps RGD1310420, anticorps Rsafd1, anticorps AW125391, anticorps im:6898509, anticorps wu:fb74d01, anticorps zgc:153368, anticorps tRNA-yW synthesizing protein 1 homolog (S. cerevisiae), anticorps S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase, anticorps tRNA-yW synthesizing protein 1 homolog S homeolog, anticorps tRNA-yW synthesizing protein 1 homolog, anticorps TYW1, anticorps LOC100354908, anticorps tyw1.S, anticorps Tyw1, anticorps tyw1

Sujet: TYW1, also known as TYW1A, RSAFD1 or YPL207W, is a 732 amino acid protein containing one flavodoxin-like domain that participates in the wybutosine-tRNA (Phe) biosynthesis pathway.Wybutosine (yW) is a hypermodified guanosine at the 3-prime position adjacent to the anticodon of phenylalanine tRNA that stabilizes codon-anticodon interactions during decoding on the ribosome.TYW1 is involved in a multistep enzymatic reaction that stabilizes codon-anticodon base-pairing during the ribosomal decoding process, thereby ensuring correct translation.TYW1 binds to one 4Fe-4S cluster and is located on human chromosome 7.Defects in some of the genes on chromosome 7 have been linked to Osteogenesis imperfecta, Williams-Beuren syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome, suggesting that TYW1 may play a role in these conditions
Synonyms: TYW1, Radical S-adenosyl methionine and flavodoxin domain-containing protein 1, RSAFD1, tRNA wybutosine-synthesizing protein 1 homolog, TYW1A, YPL207W

NCBI Accession: NP_060734