LRFN1 anticorps (C-Term)

N° du produit ABIN1887349

Détail du produit anti-LRFN1 anticorps

Antigène: LRFN1 (Leucine Rich Repeat and Fibronectin Type III Domain Containing 1 (LRFN1))

Épitope: C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LRFN1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Réactivité croisée (Details): This antibody is predicted to not cross-react with other members of the LRFN family.

Purification: Affinity chromatography purified via peptide column

Immunogène: LRFN1 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human LRFN1.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Conseil sur la manipulation: Avoid freezing and thawing repeatly.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Détails sur LRFN1

Antigène: LRFN1 (Leucine Rich Repeat and Fibronectin Type III Domain Containing 1 (LRFN1))

Autre désignation: LRFN1 (LRFN1 Produits)

Synonymes: anticorps SALM2, anticorps BC004018, anticorps Semo1, anticorps leucine rich repeat and fibronectin type III domain containing 1, anticorps LRFN1, anticorps Lrfn1

Sujet: LRFN1 is one of a family of five transmembrane glycoproteins that are highly expressed in neuronal tissues.LRFN proteins share leucine-rich repeat (LRR)-immunoglobulin-like (Ig)-fibronectin type III (Fn)-transmembrane domain structure with other members of the LRR-Ig-Fn protein superfamily such as the Slitrk family of proteins.Expression of LRFN1, -3, and -4 mRNA was detected in embryonic neuronal cells, while Lrfn2 and Lrfn5 expression was primarily restricted to more mature cells.LRFN1, -2, and -4 bound to PDZ domains of postsynaptic PSD95, re-distributing PSD95 to the cell periphery.It has been suggested that the Lrfn proteins play a role in the developing and/or mature vertebrate nervous system.At least two isoforms of LRFN1 are known to exist.
Synonyms: Leucine-rich repeat and fibronectin typeIII domain-containing protein 1, synaptic adhesion-like molecule 2

UniProt: Q9P244

Pathways: Synaptic Membrane