CIDEB anticorps (C-Term)

N° du produit ABIN1887378

Détail du produit anti-CIDEB anticorps

Antigène: CIDEB (Cell Death-Inducing DFFA-Like Effector B (CIDEB))

Épitope: C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CIDEB est non-conjugé

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Réactivité croisée (Details): CIDE-B antibody has no cross activity to CIDE-A.

Purification: Affinity chromatography purified via peptide column

Immunogène: Peptide corresponding to 15 amino acids near the carboxy terminus of human CIDE-B.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Conseil sur la manipulation: Avoid freezing and thawing repeatly.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Détails sur CIDEB

Antigène: CIDEB (Cell Death-Inducing DFFA-Like Effector B (CIDEB))

Autre désignation: CIDE-B (CIDEB Produits)

Synonymes: anticorps Cide-b, anticorps 1110030C18Rik, anticorps AI790179, anticorps CIDE-B, anticorps cell death-inducing DFFA-like effector b, anticorps cell death activator CIDE-B, anticorps cell death-inducing DNA fragmentation factor, alpha subunit-like effector B, anticorps cideb, anticorps CIDEB, anticorps Cide-b, anticorps Cideb

Sujet: Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands.Cell death signals are transduced by death domain containing adapter molecules and members of the caspase family of proteases.These death signals finally cause the degradation of chromosomal DNA by activated DNase.DFF45/ICAD has been identified as inhibitor of caspase activated DNase DFF40/CAD.DFF45 related proteins CIDE-A and CIDE-B (for cell death-inducing DFF-like effector A and B) were recently identified.CIDE contains a new type of domain termed CIDE-N, which has high homology with the regulatory domains of DFF45/ICAD and DFF40/CAD.Expression of CIDE-B induces apoptosis, which is inhibited by DFF45.CIDE-B is a DFF45-inhibitable effector that promotes cell death and DNA fragmentation.CIDE-B is expressed mainly in liver and at lower levels in spleen, kidney, peripheral blood lymphocytes and bone marrow.
Synonyms: Cell death-inducing DFF-like effector B