LRRC1 anticorps (C-Term)

N° du produit ABIN1887379

Détail du produit anti-LRRC1 anticorps

Antigène: LRRC1 (Leucine Rich Repeat Containing 1 (LRRC1))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LRRC1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Purification: Affinity chromatography purified via peptide column

Immunogène: Peptide corresponding to 15 amino acids near the carboxy terminus of human Lano.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Conseil sur la manipulation: Avoid freezing and thawing repeatly.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Détails sur LRRC1

Antigène: LRRC1 (Leucine Rich Repeat Containing 1 (LRRC1))

Autre désignation: Lano (LRRC1 Produits)

Synonymes: anticorps LRRC1, anticorps LANO, anticorps dJ523E19.1, anticorps A430093J20Rik, anticorps AU016091, anticorps D030059I21, anticorps mKIAA4018, anticorps leucine rich repeat containing 1, anticorps Lrrc1, anticorps LRRC1

Sujet: Lano is a member of the LAP (leucine-rich repeats and PDZ) family of proteins that also includes Densin-180, Erbin, and hScribble.The LAP proteins generally contain multiple leucine-rich repeat (LRR) domains which serve to target them to the basolateral membrane of epithelial cells.Lano is unique in that it alone does not possess one or more PDZ (PSD95/DLG/ZO-1) domains as do the other members of the LAP family.However, it can bind to the PDZ domain of Erbin in addition to those of membrane-associated and guanylate kinase (MAGUK) proteins which regulate adhesion and plasticity at cell junctions.It has been suggested that it is through these interaction that these LAP proteins participate in the maintenance of proper embryonic development and integrity of epithelial tissues.