LY9 anticorps (C-Term)

N° du produit ABIN1887433

Détail du produit anti-LY9 anticorps

Antigène: LY9 (CD229) (Lymphocyte Antigen 9 (CD229))

Épitope: C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LY9 est non-conjugé

Application: Western Blotting (WB), ELISA

Réactivité croisée (Details): At least three isoforms of SLAMF3 are known to exist. SLAMF3 antibody is predicted to not cross-react with other SLAM protein family members.

Purification: Affinity chromatography purified via peptide column

Immunogène: SLAMF3 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human SLAMF3.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Conseil sur la manipulation: Avoid freezing and thawing repeatly.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Détails sur LY9

Antigène: LY9 (CD229) (Lymphocyte Antigen 9 (CD229))

Autre désignation: SLAMF3 (CD229 Produits)

Synonymes: anticorps LY9, anticorps CD229, anticorps SLAMF3, anticorps hly9, anticorps mLY9, anticorps AI893573, anticorps Lgp100, anticorps Ly-9, anticorps T100, anticorps lymphocyte antigen 9, anticorps LY9, anticorps Ly9

Sujet: The signaling lymphocyte-activation molecule family member 3 (SLAMF3), also known as LY9, is a cell surface receptor that is expressed on T and B lymphocytes and belongs to the CD150/SLAMF1 receptor family.SLAMF3 was identified through a yeast two-hybrid screening in which SLAMF3 bound to the X-linked lymphoproliferative disease gene product SAP, suggesting that in activated T cells, SLAMF3 signaling can be triggered SAP.Its expression on the cell surface appears to be regulated via its interaction with the clathrin-associated adaptor complex 2 (AP-2).Despite its similarity to SLAMF1 in structure and interactions with SAP, SLAMF3-deficient mice do not exhibit phenotypic characteristics associated with SLAMF1- and SAP-deficient mice, suggesting that SLAMF3 plays other roles in T cell activation.
Synonyms: Signaling lymphocytic activation molecule family member 3, lymphocyte antigen 9, LY9, hly9, CD229

NCBI Accession: NP_1769

Pathways: BCR Signaling