PKDCC anticorps (Center)

N° du produit ABIN1887552

Détail du produit anti-PKDCC anticorps

Antigène: PKDCC (Protein Kinase Domain Containing, Cytoplasmic Homolog (Mouse) (PKDCC))

Épitope: Center

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PKDCC est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Purification: Affinity chromatography purified via peptide column

Immunogène: 15 amino acid peptide from near the center of human VLK.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Conseil sur la manipulation: Avoid freezing and thawing repeatly.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Détails sur PKDCC

Antigène: PKDCC (Protein Kinase Domain Containing, Cytoplasmic Homolog (Mouse) (PKDCC))

Autre désignation: VLK (PKDCC Produits)

Synonymes: anticorps SGK493, anticorps Vlk, anticorps AI115348, anticorps AW548124, anticorps Adtk1, anticorps ESTM17, anticorps MAd1, anticorps Sgk493, anticorps X83346, anticorps RGD1311939, anticorps protein kinase domain containing, cytoplasmic, anticorps PKDCC, anticorps Pkdcc

Sujet: VLK was identified as a novel protein kinase that was induced after the differentiation of cultured embryonic stem cells into mesendoderm.It has no homologs in invertebrates, but is highly conserved in vertebrate species although it does not belong to any known protein kinase groups.VLK is initially expressed in E-cadherin-positive anterior visceral endoderm and mesendoderm, but its expression is later confined to E-cadherin-negative mesenchyme.It is enriched in the Golgi apparatus and is thought to regulate the rate of protein export from the Golgi.Targeted disruption of VLK in mice leads to a defect in lung development and neonatal lethality.It has been suggested that mutations in VLK may be associated with the allergic condition atopy.
Synonyms: Vertebrate lonesome kinase, protein kinase domain containing cytoplasmic homolog, PKDCC, SGK439