PHOX2B anticorps (Center)

N° du produit ABIN1887561

Détail du produit anti-PHOX2B anticorps

Antigène: PHOX2B (Paired-Like Homeobox 2b (PHOX2B))

Épitope: Center

Reactivité: Souris, Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PHOX2B est non-conjugé

Application: Western Blotting (WB), ELISA

Réactivité croisée (Details): PHOX2B antibody is predicted to not cross-react with other paired homeobox family members.

Purification: Affinity chromatography purified via peptide column

Immunogène: 15 amino acid peptide near the center of human PHOX2B.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Conseil sur la manipulation: Avoid freezing and thawing repeatly.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Détails sur PHOX2B

Antigène: PHOX2B (Paired-Like Homeobox 2b (PHOX2B))

Autre désignation: PHOX2B (PHOX2B Produits)

Synonymes: anticorps phox2, anticorps xphox2b, anticorps phox2b, anticorps PHOX2B, anticorps pmx2b, anticorps nbphox, anticorps NBLST2, anticorps NBPhox, anticorps PMX2B, anticorps Dilp1, anticorps Pmx2b, anticorps paired-like homeobox 2b, anticorps paired like homeobox 2b S homeolog, anticorps paired-like homeobox 2bb, anticorps paired like homeobox 2b, anticorps phox2b, anticorps phox2b.S, anticorps phox2bb, anticorps PHOX2B, anticorps Phox2b

Sujet: PHOX2A and PHOX2B (Paired mesoderm homeobox protein) are closely related, paired-homeodomain transcription factors that function as determinants of the noradrenergic phenotype during embryogenesis.PHOX2 proteins are crucial for the regulation of endogenous hydroxylases in neural crest cells and promote sympathetic neuron generation.Human PHOX2B contains one DNA binding homeobox domain and is required for the differentiation of all central and nonperipheral noradrenergic centers in the brain.In contrast, PHOX2A controls only the differentiation of the main noradrenergic center of the brain.Regulation of PHOX2 may have therapeutic utility in aging or disorders involving degeneration of noradrenergic neurons .
Synonyms: Paired-like homeobox 2B, Paired mesoderm homeobox protein 2B, PMX2B, Neuroblastoma Phox, NBLST2, NBPhox

NCBI Accession: NP_003915