PRICKLE2 anticorps (Center)

N° du produit ABIN1887562

Détail du produit anti-PRICKLE2 anticorps

Antigène: PRICKLE2 (Prickle Homolog 2 (PRICKLE2))

Épitope: Center

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PRICKLE2 est non-conjugé

Application: Western Blotting (WB), ELISA

Réactivité croisée (Details): Two isoforms of PRICKLE2 are known to exist. PRICKLE2 antibody is predicted to not cross-react with other PRICKLE protein family members.

Purification: Affinity chromatography purified via peptide column

Immunogène: 15 amino acid peptide near the center of human PRICKLE2.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Conseil sur la manipulation: Avoid freezing and thawing repeatly.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Détails sur PRICKLE2

Antigène: PRICKLE2 (Prickle Homolog 2 (PRICKLE2))

Autre désignation: PRICKLE2 (PRICKLE2 Produits)

Synonymes: anticorps EPM5, anticorps 6230400G14Rik, anticorps 6720451F06Rik, anticorps mpk2, anticorps cb886, anticorps im:7138215, anticorps pk2, anticorps prickle planar cell polarity protein 2, anticorps prickle homolog 2b, anticorps PRICKLE2, anticorps Prickle2, anticorps prickle2b

Sujet: PRICKLE2, also known as Pk2 or EPM5, is a member of a highly conserved protein family that function in the noncanonical WNT signaling pathway which regulates intracellular calcium release and planar cell polarity.Both PRICKLE2 and the related protein PRICKLE1 are expressed in postmitotic neurons and promote neurite outgrowth , and both proteins promote neurite outgrowth via the Dishevelled dependent pathway in C1300 cells.PRICKLE2 localizes to the postsynaptic density and interacts with PSD-95 and NMDA receptors.Defects in the gene encoding PRICKLE2 are associated with autosomal recessive progressive myoclonic epilepsy.
Synonyms: REST, NRSF-interacting LIM domain protein 1, Pk2, EPM5

NCBI Accession: NP_942559