AIFM3 anticorps (Center)

N° du produit ABIN1887580

Détail du produit anti-AIFM3 anticorps

Antigène: AIFM3 (Apoptosis-Inducing Factor, Mitochondrion-Associated, 3 (AIFM3))

Épitope: Center

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AIFM3 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Affinity chromatography purified via peptide column

Immunogène: 16 amino acid peptide from near the center of human AIFM3.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Conseil sur la manipulation: Avoid freezing and thawing repeatly.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Détails sur AIFM3

Antigène: AIFM3 (Apoptosis-Inducing Factor, Mitochondrion-Associated, 3 (AIFM3))

Autre désignation: AIFM3 (AIFM3 Produits)

Synonymes: anticorps nfrl-A, anticorps MGC84340, anticorps AIFM3, anticorps LOC100150876, anticorps 2810401C16Rik, anticorps AI840249, anticorps Aifl, anticorps RGD1306028, anticorps AIFL, anticorps apoptosis inducing factor, mitochondria associated 3 L homeolog, anticorps apoptosis inducing factor, mitochondria associated 3, anticorps apoptosis-inducing factor, mitochondrion-associated 3, anticorps aifm3.L, anticorps AIFM3, anticorps aifm3, anticorps Aifm3

Sujet: Apoptosis, also known as programmed cell death, plays major roles in development and normal tissue turnover in addition to tumor formation.Recently a protein similar to the apoptosis-inducing factor (AIF) was cloned and designated AIFL (also known as AIFM3).AIFM3 is expressed ubiquitously and is predominantly localized to the inner membranes of mitochondria.Unlike AIF, AIFM3 does not translocate to the nucleus upon induction of apoptosis.However, overexpression of AIFM3, like AIF, induced cytochrome c release from the mitochondria, cleavage of caspase 3, and ultimately apoptosis, indicating AIFM3 induces apoptosis through caspase activation.Multiple isoforms of AIFM3 are known to exist.
Synonyms: Apoptosis-inducing factor mitochondrion-associated 3, AIFL

UniProt: Q96NN9

Pathways: Positive Regulation of Endopeptidase Activity, Cell RedoxHomeostasis