SPRED3
Reactivité: Humain, Souris
WB, IHC, ELISA
Hôte: Lapin
Polyclonal
PE
Restrictions
For Research Use only
Format
Liquid
Buffer
PBS containing 0.02 % sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Conseil sur la manipulation
Avoid freezing and thawing repeatly.
Stock
4 °C/-20 °C
Stockage commentaire
Store at 4 °C for short term use.Store at -20 °C for long term preservation.
Spred3 is a member of the Sprouty family, a group of proteins that act as negative regulators during development.Like Spred1 and Spred2, Spred3 contains and EVH1 domain in its amino terminus and a Sprouty-related cysteine-rich (SPR) domain in its C-terminus, but does not possess a functional c-kit binding domain (KBD).The Spred proteins have also been implicated in the negative feedback regulation of FGF signaling in embryogenesis and angiogenesis.Although Spred3 was initially reported to be expressed in brain, at least one report also indicates that Spred3 can be found in liver.At least two isoforms of Spred3 are known to exist. Synonyms: Sprouty-related EVH1 domain-containing protein 3, EVE-3