ANAPC13 anticorps (Center)

N° du produit ABIN1887649

Détail du produit anti-ANAPC13 anticorps

Antigène: ANAPC13 (Anaphase Promoting Complex Subunit 13 (ANAPC13))

Épitope: Center

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ANAPC13 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Affinity chromatography purified via peptide column

Immunogène: 17 amino acid peptide near the center of human APC13.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Conseil sur la manipulation: Avoid freezing and thawing repeatly.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Détails sur ANAPC13

Antigène: ANAPC13 (Anaphase Promoting Complex Subunit 13 (ANAPC13))

Autre désignation: APC13 (ANAPC13 Produits)

Synonymes: anticorps APC13, anticorps SWM1, anticorps 1810004D07Rik, anticorps anaphase promoting complex subunit 13, anticorps ANAPC13, anticorps Bm1_31995, anticorps LOAG_01662, anticorps Anapc13

Sujet: Cell cycle regulated protein ubiquitination and degradation within subcellular domains is thought to be essential for the normal progression of mitosis.APC13 is a highly conserved component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle.APC/C is responsible for degrading anaphase inhibitors, mitotic cyclins, and spindle-associated proteins ensuring that events of mitosis take place in proper sequence.The individual APC/C components mRNA and protein levels are expressed at approximately the same levels in most tissues and cell lines, suggesting that they perform their functions as part of a complex.APC13 promotes the stable association of APC3/Cdc27 and APC6/Cdc16 with the APC/C.
Synonyms: Anaphase promoting complex 13, ANAPC13, Swm1

NCBI Accession: NP_056206