PRR5L anticorps (Center)

N° du produit ABIN1887660

Détail du produit anti-PRR5L anticorps

Antigène: PRR5L (Proline Rich 5 Like (PRR5L))

Épitope: Center

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PRR5L est non-conjugé

Application: Western Blotting (WB), ELISA

Réactivité croisée (Details): At least three isoforms of PRR5L are known to exist, this antibody will recognize only isoforms a and b. PRR5L antibody will not cross-react with PPR5.

Purification: Affinity chromatography purified via peptide column

Immunogène: 17 amino acid peptide near the center of human PRR5L.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Conseil sur la manipulation: Avoid freezing and thawing repeatly.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Détails sur PRR5L

Antigène: PRR5L (Proline Rich 5 Like (PRR5L))

Autre désignation: PRR5L (PRR5L Produits)

Synonymes: anticorps PROTOR2, anticorps 2600010E01Rik, anticorps 4833411O04Rik, anticorps Protor-2, anticorps Protor2, anticorps RGD1309969, anticorps PRR5L, anticorps FLJ14213, anticorps proline rich 5 like, anticorps PRR5L, anticorps Prr5l, anticorps prr5l

Sujet: Proline-rich protein 5-like (PRR5L), also known as Protor-2, is structurally similar to PRR5 and also binds to the mTOR complex 2 (mTORC2).PRR5L is not required for mTORC2 integrity or kinase activity, but dissociates from mTORC2 upon knockdown of tuberous sclerosis complex 1 (TSC1) and TSC2.Knockdown of PRR5L reduced apoptosis in mTORC2 deficient cells as well as cells where mTOR was active, suggesting that mTORC2-dissociated PRR5L may promote apoptosis, and thus play a role in the balance between cell growth and cell death.
Synonyms: Proline-rich protein 5-like, Protor-2, PROTOR2

NCBI Accession: NP_001153639