RABGEF1 anticorps (Center)

N° du produit ABIN1887724

Détail du produit anti-RABGEF1 anticorps

Antigène: RABGEF1 (RAB Guanine Nucleotide Exchange Factor (GEF) 1 (RABGEF1))

Épitope: Center

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RABGEF1 est non-conjugé

Application: Western Blotting (WB), ELISA

Réactivité croisée (Details): At least four isoforms of RABEX5 are known to exist, this antibody will recognize all four. RABEX5 antibody is predicted to not cross-react with other LRRFIP family members.

Purification: Affinity chromatography purified via peptide column

Immunogène: 19 amino acid peptide near the center terminus of human RABEX5.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Conseil sur la manipulation: Avoid freezing and thawing repeatly.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Détails sur RABGEF1

Antigène: RABGEF1 (RAB Guanine Nucleotide Exchange Factor (GEF) 1 (RABGEF1))

Autre désignation: RABEX5 (RABGEF1 Produits)

Synonymes: anticorps Rab5ef, anticorps Rabex5, anticorps Rin2, anticorps RABEX5, anticorps rabex-5, anticorps rabgef1, anticorps RAB guanine nucleotide exchange factor (GEF) 1, anticorps RAB guanine nucleotide exchange factor 1, anticorps RAB guanine nucleotide exchange factor (GEF) 1 L homeolog, anticorps Rabgef1, anticorps RABGEF1, anticorps rabgef1.L

Sujet: RABEX5 is a guanine nucleotide exchange factor (GEF) that forms a complex with rabaptin-5 and specifically activates Rab5, a small GTPase that plays an essential role in endocytic traffic.RABEX-5 is thought to also interact with another member of the Rab family, Rab22, which targets RABEX5 to early endosomes, allowing it to activate Rab5 and thereby promote Rab5-mediated endosome fusion.
Synonyms: Rab5 GDP, GTP exchange factor, RABGEF1

NCBI Accession: NP_055319

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process