Anosmin anticorps (Center)

N° du produit ABIN1887739

Détail du produit anti-Anosmin anticorps

Antigène: Anosmin (ANOS1)

Épitope: Center

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Anosmin est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Affinity chromatography purified via peptide column

Immunogène: Anosmin antibody was raised against an 18 amino acid peptide near the center of human Anosmin.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Conseil sur la manipulation: Avoid freezing and thawing repeatly.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Détails sur Anosmin

Antigène: Anosmin (ANOS1)

Abstract: ANOS1 Produits

Synonymes: anticorps ADMLX, anticorps HH1, anticorps HHA, anticorps KAL, anticorps KALIG-1, anticorps KMS, anticorps WFDC19, anticorps anosmin 1, anticorps ANOS1

Sujet: Mutations in Anosmin-1, an extracellular matrix-associated glycosylated protein, have been linked with Kallmann Syndrome (KS), an X-linked genetic disorder characterized by loss of smell caused by abnormal olfactory bulb development and delayed puberty caused by disrupted migration of the gonadotropin-releasing hormone neuron.Anosmin-1 has been shown to directly bind FGFR1 via its N-terminal cysteine-rich domain, whey-acidic protein-like domain, and its first FnIII repeat with the D2 and D3 ectodomains of FGFR1.It is thought that Anosmin-1 can modulate FGFR1 signaling and have opposing effects on the formation and activation of FGF2-FGFR1-heparing complex.
Synonyms: Anosmin, Anosmin-1, KALIG-1, KAL1, HHA, KMS,

NCBI Accession: NP_000207