DACT2 anticorps (N-Term)

N° du produit ABIN1887827

Détail du produit anti-DACT2 anticorps

Antigène: DACT2 (Dapper, Antagonist of beta-Catenin 2 (DACT2))

Épitope: N-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DACT2 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Purification: Affinity chromatography purified via peptide column

Immunogène: 12 amino acid peptide from near the amino terminus of human DACT2.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Conseil sur la manipulation: Avoid freezing and thawing repeatly.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Détails sur DACT2

Antigène: DACT2 (Dapper, Antagonist of beta-Catenin 2 (DACT2))

Autre désignation: Dact2 (DACT2 Produits)

Synonymes: anticorps 2900084M21Rik, anticorps A630024E20, anticorps Dpr2, anticorps Frd2, anticorps dapper2, anticorps C6orf116, anticorps DAPPER2, anticorps DPR2, anticorps RP11-503C24.7, anticorps bA503C24.7, anticorps dishevelled binding antagonist of beta catenin 2, anticorps dishevelled-binding antagonist of beta-catenin 2, anticorps DACT2, anticorps Dact2

Sujet: The Wnt signaling cascade is a conserved process in multicellular animals that plays important roles during development and can contribute to cancer and other diseases.Many members of this pathway are also expressed in the postnatal tissues such as brain.One such protein is Dact2, a member of the Dact protein family that was initially identified through binding to Disheveled (Dvl), a cytoplasmic protein essential to Wnt signaling.Dact2 is most prominent during the development of the thymus kidneys, and salivary gland.Dact2 is thought to play a role distinct from that of Dact1 with Dact2 having a greater impact on a beta-catenin-independent process termed planar cell polarity/convergent-extension signaling.Furthermore, Dact2 but not Dact1 can inhibit Nodal signaling by promoting the endocytic degradation of TGF-beta receptors.At least two isoforms of Dact2 are known to exist.
Synonyms: Dapper homolog 2, Dapper antagonist of beta-catenin 2

NCBI Accession: NP_999627