BAG1 anticorps (N-Term)

N° du produit ABIN1887852

Détail du produit anti-BAG1 anticorps

Antigène: BAG1 (BCL2-Associated Athanogene (BAG1))

Épitope: N-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BAG1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Purification: Affinity chromatography purified via peptide column

Immunogène: 14 amino acid peptide from near the amino terminus of human BAG-1.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Conseil sur la manipulation: Avoid freezing and thawing repeatly.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Détails sur BAG1

Antigène: BAG1 (BCL2-Associated Athanogene (BAG1))

Autre désignation: BAG-1 (BAG1 Produits)

Synonymes: anticorps BAG-1, anticorps HAP, anticorps RAP46, anticorps Rap46, anticorps Bag-1, anticorps ATBAG1, anticorps BCL-2-associated athanogene 1, anticorps MSG15.15, anticorps MSG15_15, anticorps im:7148830, anticorps si:dkey-216e9.4, anticorps BCL2 associated athanogene 1, anticorps putative bcl2-associated athanogene, anticorps BCL2-associated athanogene 1, anticorps Bcl2 associated athanogene 1, anticorps BAG family molecular chaperone regulator 1, anticorps BCL-2-associated athanogene 1, anticorps BAG1, anticorps Smp_005900, anticorps Bag1, anticorps bag-1, anticorps LOC781741, anticorps bag1

Sujet: Bcl-2-associated athanogene 1 (BAG-1) was first identified as an anti-apoptotic bcl-2-binding protein.Later it was found to bind the molecular chaperones Hsp70 and Hsc70 through its carboxy-terminal sequence (termed the Bag domain), resulting in the inhibition of the refolding activity of these chaperones.It is thought that by binding and inhibiting these molecular chaperones, BAG-1is able to modulate the expression level of proteins requiring chaperones to fold correctly.One such group of proteins that are affected is glucocorticoid receptors.Other reports have suggested that the level of BAG-1 expression correlates with the aggressiveness of various cancers.Multiple isoforms of BAG-1 are known to exist.
Synonyms: Bcl-2-binding athanogene-1, receptor-associated protein 46, RAP46

NCBI Accession: NP_004314