STEAP3 anticorps (N-Term)

N° du produit ABIN1887914

Détail du produit anti-STEAP3 anticorps

Antigène: STEAP3 (STEAP Family Member 3, Metalloreductase (STEAP3))

Épitope: N-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp STEAP3 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Réactivité croisée (Details): This STEAP3 antibody does not cross-react with other STEAP proteins.

Purification: Affinity chromatography purified via peptide column

Immunogène: 15 amino acid peptide from near the amino terminus of human STEAP3.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Conseil sur la manipulation: Avoid freezing and thawing repeatly.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Détails sur STEAP3

Antigène: STEAP3 (STEAP Family Member 3, Metalloreductase (STEAP3))

Autre désignation: STEAP3 (STEAP3 Produits)

Synonymes: anticorps STEAP3, anticorps 1010001D01Rik, anticorps Tsap6, anticorps pHyde, anticorps AHMIO2, anticorps STMP3, anticorps TSAP6, anticorps dudlin-2, anticorps STEAP3 metalloreductase, anticorps STEAP family member 3, anticorps STEAP3, anticorps steap3, anticorps Steap3

Sujet: The six-transmembrane epithelial antigen of prostate 3 (STEAP3) is a member of a family of metalloreductases identified as cell-surface antigens in prostate tissue.Similar to two other members of the STEAP family (STEAP 2 and STEAP4), STEAP3 promotes both iron and copper reduction.STEAP3 is highly expressed in hematopoietic tissues and colocalizes with the transferrin endosome.Overexpression of STEAP3 stimulates iron reduction, mice lacking STEAP3 are deficient in erythroid ferrireductase activity, suggesting that STEAP3 is an endosomal ferrireductase required for transferrin-dependent iron uptake in erythroid cells.
Synonyms: Six transmembrane epithelial antigen of prostate 3, dudulin-2

Pathways: Transition Metal Ion Homeostasis