SLC39A1 anticorps (N-Term)

N° du produit ABIN1888014

Détail du produit anti-SLC39A1 anticorps

Antigène: SLC39A1 (Solute Carrier Family 39 (Zinc Transporter), Member 1 (SLC39A1))

Épitope: N-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SLC39A1 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Purification: Affinity chromatography purified via peptide column

Immunogène: 16 amino acid peptide near the amino terminus of human ZIP1.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Conseil sur la manipulation: Avoid freezing and thawing repeatly.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Détails sur SLC39A1

Antigène: SLC39A1 (Solute Carrier Family 39 (Zinc Transporter), Member 1 (SLC39A1))

Autre désignation: ZIP1 (SLC39A1 Produits)

Synonymes: anticorps cb629, anticorps DrZIP1, anticorps sb:cb629, anticorps zgc:111852, anticorps frzip1p, anticorps zip1, anticorps zirtl, anticorps ZIP1, anticorps ZIRTL, anticorps Zip1, anticorps Zirtl, anticorps solute carrier family 39 (zinc transporter), member 1, anticorps solute carrier family 39 member 1, anticorps solute carrier family 39 member 1 L homeolog, anticorps slc39a1, anticorps Slc39a1, anticorps SLC39A1, anticorps slc39a1.L

Sujet: ZIP1, also known as ZIRTL (zinc-iron regulated transporter-like), is the first mammalian member of a family of divalent ion transporters.Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation.ZIP1 expression is markedly downregulated in a number of cancerous tissues and is thought to function as a tumor suppressor gene in prostate cancer.More recent studies have shown that overexpression of ZIP1 and concomitant increased levels of intracellular zinc in PC-3 cells cause a significant inhibition of NF-kappaB, leading to down-regulation of the antiapoptotic protein Bcl-2, Bcl-XL, and the apoptosis inhibitor XIAP, reducing the malignant potential of prostate cancer cells in vitro and in vivo.
Synonyms: Solute carrier family 39 member A1, Slc39A1, ZIRTL

NCBI Accession: NP_055252

Pathways: Autophagy