Transportin 3 anticorps (N-Term)

N° du produit ABIN1888081

Détail du produit anti-Transportin 3 anticorps

Antigène: Transportin 3 (TNPO3)

Épitope: N-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Transportin 3 est non-conjugé

Application: ELISA, Western Blotting (WB)

Purification: Affinity chromatography purified via peptide column

Immunogène: 18 amino acid peptide from near the amino terminus of human TNPO3.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Conseil sur la manipulation: Avoid freezing and thawing repeatly.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Détails sur Transportin 3

Antigène: Transportin 3 (TNPO3)

Autre désignation: TNPO3 (TNPO3 Produits)

Synonymes: anticorps zgc:55409, anticorps tnpo3, anticorps MGC82948, anticorps TNPO3, anticorps DKFZp459J2330, anticorps IPO12, anticorps MTR10A, anticorps TRN-SR, anticorps TRN-SR2, anticorps TRNSR, anticorps 5730544L10Rik, anticorps C430013M08Rik, anticorps C81142, anticorps D6Ertd313e, anticorps Trn-SR, anticorps mKIAA4133, anticorps transportin 3, anticorps transportin 3 S homeolog, anticorps transportin-SR, anticorps tnpo3, anticorps TNPO3, anticorps tnpo3.S, anticorps Bm1_43850, anticorps LOAG_04608, anticorps Tnpo3

Sujet: TNPO3 is a member of the importin beta/transportin family of nuclear import receptors and is specific for the essential splicing factors termed SR proteins, binding specifically and directly to the arginine/serine (RS)-rich domains of these proteins.Further experiments demonstrated that this interaction occurs only when these RS domains are phosphorylated.More recently, TNPO3 was identified as an HIV dependency factor (HDF) and that depletion of TNPO3 resulted in HIV inhibition after reverse transcription but before integration, suggesting that TNPO3 may be an important drug target in HIV treatment.At least three isoforms of TNPO3 are known to exist.
Synonyms: Transportin-3, Importin-12, IPO12, TRNSR, MTR10A, TRN-SR

Pathways: Protein targeting to Nucleus