IL16 anticorps (N-Term)

N° du produit ABIN1888134

Détail du produit anti-IL16 anticorps

Antigène: IL16 (Interleukin 16 (IL16))

Épitope: N-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IL16 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Specificité: This antibody will only detect the NIL-16 isoform.

Purification: Affinity chromatography purified via peptide column

Immunogène: 20 amino acid peptide near the amino terminus of human IL-16.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Conseil sur la manipulation: Avoid freezing and thawing repeatly.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Détails sur IL16

Antigène: IL16 (Interleukin 16 (IL16))

Autre désignation: IL-16 (IL16 Produits)

Synonymes: anticorps IL16, anticorps LCF, anticorps NIL16, anticorps PRIL16, anticorps prIL-16, anticorps mKIAA4048, anticorps IL-16, anticorps interleukin 16, anticorps IL16, anticorps Il16

Sujet: IL-16 was initially identified as a chemotactic cytokine, but is now known to possess a wide range of activities.Later studies have more fully characterized IL-16 as an immunomodulatory cytokine that contributes to the regulatory process of CD4+ T cell recruitment and activation at sites of inflammation in association with asthma and several autoimmune diseases.The precursor of IL-16 (pro-IL-16) is thought to be cleaved towards the C-terminal region by Caspase-3, releasing a 20 kDa active form that binds to and signals through CD4.Besides acting as a chemotactic cytokine, IL-16 is thought to also be involved in the regulation of T cell proliferation and multiple infectious, immune-mediated, and autoimmune inflammatory disorders including irritable bowel syndrome, systemic lupus erythematosus, and neurodegenerative disorders.At least two isoforms of IL-16 are known to exist, the longer isoform (also known as NIL-16) is detected only in neurons of the cerebellum and hippocampus.
Synonyms: Interleukin 16, leukocyte chemoattractant factor, LCF, NIL-16