STK17A anticorps (N-Term)

N° du produit ABIN1888195

Détail du produit anti-STK17A anticorps

Antigène: STK17A (serine/threonine Kinase 17a (STK17A))

Épitope: N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp STK17A est non-conjugé

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

Réactivité croisée (Details): No cross responses to DRAK2, DAP or ZIP kinases.

Purification: Affinity chromatography purified via peptide column

Immunogène: Peptide corresponding to amino acids near the amino terminus of human DRAK1.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Conseil sur la manipulation: Avoid freezing and thawing repeatly.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Détails sur STK17A

Antigène: STK17A (serine/threonine Kinase 17a (STK17A))

Autre désignation: DRAK1 (STK17A Produits)

Synonymes: anticorps STK17A, anticorps DRAK1, anticorps RDRAK1, anticorps serine/threonine kinase 17a, anticorps serine/threonine kinase 17a L homeolog, anticorps STK17A, anticorps stk17a, anticorps stk17a.L

Sujet: Apoptosis is mediated by death domain containing adapter molecules and a caspase family of proteases.Certain serine/threonine protein kinases, such as ASK-1 and RIP, are mediators of apoptosis.Two novel serine/threonine kinases that induce apoptosis were recently identified and designated DRAK1 and DRAK2 for DAP kinase-related apoptosis-inducing protein kinases.DRAKs contain an N-terminal kinase domain and a C-terminal regulation domain.Overexpression of DRAK1 induces apoptosis.DRAKs have high sequence homology to DAP and ZIP kinases, and they represent a novel family of serine/threonine kinases, which mediates apoptosis through their catalytic activities.DRAK1 is located in nucleus and the messenger RNA was ubiquitously expressed in human tissues.

Poids moléculaire: 50 kDa

UniProt: Q9UEE5