BCL10 anticorps (AA 1-143)

N° du produit ABIN1944800

Il existe 3+ publications pour ce produit. L’anticorps anti-BCL10 Monoclonal Souris est utilisé pour la détection de BCL10 dans des échantillons de Humain. Il a été validé pour WB, FACS et IHC (p).

Aperçu rapide pour BCL10 anticorps (AA 1-143) (ABIN1944800)

Antigène: BCL10 (B-Cell CLL/lymphoma 10 (BCL10))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp BCL10 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 1185CT13-2-1-2

Détail du produit anti-BCL10 anticorps

Épitope: AA 1-143

Purification: This antibody is purified through a protein G column, followed by dialysis against PBS.

Immunogène: This BCL10 antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between 1-143 amino acids from the human region of human BCL10.

Isotype: IgG1 kappa

Information d'application

Indications d'application: WB: 1:2000. IHC-P: 1:25. IHC-P: 1:25. FC: 1:25

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-BCL10 (ABIN1944800)

Koseki, Inohara, Chen, Carrio, Merino, Hottiger, Nabel, Núñez: "CIPER, a novel NF kappaB-activating protein containing a caspase recruitment domain with homology to Herpesvirus-2 protein E10." dans: The Journal of biological chemistry, Vol. 274, Issue 15, pp. 9955-61, (1999) (PubMed).

Thome, Martinon, Hofmann, Rubio, Steiner, Schneider, Mattmann, Tschopp: "Equine herpesvirus-2 E10 gene product, but not its cellular homologue, activates NF-kappaB transcription factor and c-Jun N-terminal kinase." dans: The Journal of biological chemistry, Vol. 274, Issue 15, pp. 9962-8, (1999) (PubMed).

Yan, Lee, Schilbach, Goddard, Dixit: "mE10, a novel caspase recruitment domain-containing proapoptotic molecule." dans: The Journal of biological chemistry, Vol. 274, Issue 15, pp. 10287-92, (1999) (PubMed).

Détails sur BCL10

Antigène: BCL10 (B-Cell CLL/lymphoma 10 (BCL10))

Autre désignation: BCL10

Sujet: Promotes apoptosis, pro-caspase-9 maturation and activation of NF-kappa-B via NIK and IKK. May be an adapter protein between upstream TNFR1-TRADD-RIP complex and the downstream NIK-IKK-IKAP complex. Is a substrate for MALT1.

Poids moléculaire: 26252

ID gène: 8915

UniProt: O95999

Pathways: TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Tube Formation, Positive Regulation of Endopeptidase Activity, BCR Signaling, Ubiquitin Proteasome Pathway, S100 Proteins