Ube2t anticorps

N° du produit ABIN1944867

Détail du produit anti-Ube2t anticorps

Antigène: Ube2t (Ubiquitin-Conjugating Enzyme E2T (Ube2t))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Ube2t est non-conjugé

Application: Western Blotting (WB)

Isotype: IgG

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Stock: 4 °C,-20 °C

Détails sur Ube2t

Antigène: Ube2t (Ubiquitin-Conjugating Enzyme E2T (Ube2t))

Autre désignation: UBE2T (Ube2t Produits)

Synonymes: anticorps PIG50, anticorps UBE2T, anticorps 2700084L22Rik, anticorps C80607, anticorps RGD1310816, anticorps hspc150, anticorps wu:fj86h11, anticorps zgc:153687, anticorps ubiquitin conjugating enzyme E2 T, anticorps ubiquitin-conjugating enzyme E2T, anticorps ubiquitin conjugating enzyme E2T S homeolog, anticorps ubiquitin-conjugating enzyme E2T (putative), anticorps UBE2T, anticorps Ube2t, anticorps ube2t.S, anticorps ube2t

Sujet: Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. Catalyzes monoubiquitination. Involved in mitomycin-C (MMC)-induced DNA repair: acts as a specific E2 ubiquitin-conjugating enzyme for the Fanconi anemia complex by associating with E3 ubiquitin-protein ligase FANCL and catalyzing monoubiquitination of FANCD2, a key step in the DNA damage pathway. Also mediates monoubiquitination of FANCL and FANCI. May contribute to ubiquitination and degradation of BRCA1. In vitro able to promote polyubiquitination using all 7 ubiquitin Lys residues, but may prefer 'Lys-11'-, 'Lys-27'-, 'Lys-48'- and 'Lys-63'-linked polyubiquitination.

Poids moléculaire: 22521 Da

ID gène: 29089

UniProt: Q9NPD8

Pathways: Chromatin Binding