CDC25C anticorps (pSer216)

N° du produit ABIN196818

Cet anticorps anti-CDC25C Polyclonal Lapin (ABIN196818) détecte spécifiquement CDC25C dans WB, IF et IHC (p). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour CDC25C anticorps (pSer216) (ABIN196818)

Antigène: CDC25C (Cell Division Cycle 25 Homolog C (S. Pombe) (CDC25C))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CDC25C est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-CDC25C anticorps

Épitope: pSer216

Specificité: This antibody detects endogenous levels of CDC25C only when phosphorylated at Serine 216.

Purification: Immunoaffinity Chromatography

Immunogène: Synthetic phosphopeptide derived from human cdc25C around the phosphorylation site of Serine 216 (S-P-Sp-M-P).

Information d'application

Indications d'application: Suitable for use in Immunohistochemistry (1/50approx. 1/100).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % Sodium Azide and 50 % Glycerol

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store the antibody (in aliquots) at -20 °C.

Détails sur CDC25C

Antigène: CDC25C (Cell Division Cycle 25 Homolog C (S. Pombe) (CDC25C))

Autre désignation: CDC25C

Sujet: Cdc25C is a tyrosine phosphatase and belongs to the Cdc25 phosphatase family. It has been highly conserved during evolution and it plays a key role in the regulation of cell division. It directs dephosphorylation of cyclin B-bound CDC2 and triggers entry into mitosis. It is also thought to suppress p53-induced growth arrest. Cdc25C is mainly expressed in G2 phase. Multiple alternatively spliced transcript variants of this gene have been described, however, the full-length nature of many of them is not known.Synonyms: Cell Division Cycle 25C, Dual specificity phosphatase Cdc25C, M-phase inducer phosphatase 3

ID gène: 995

NCBI Accession: NP_001781

UniProt: P30307

Pathways: Cycle Cellulaire, M Phase