TLR4 anticorps

N° du produit ABIN198155

L’anticorps Souris Monoclonal anti-TLR4 a été validé pour FACS, IHC, IP, Neut et IHC (fro). Il convient pour détecter TLR4 dans des échantillons de Humain et Singe.

Aperçu rapide pour TLR4 anticorps (ABIN198155)

Antigène: TLR4 (Toll-Like Receptor 4 (TLR4))

Reactivité: Humain, Singe

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TLR4 est non-conjugé

Application: Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP), Neutralization (Neut), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: HTA125

Détail du produit anti-TLR4 anticorps

Specificité: Reacts preferentially, especially in Flow Cytometry, with human TLR4 (CD284) that is associated with MD-2. This clone is a TLR4 (CD284) function-blocking antibody that is useful for studies on the role of TLR4 (CD284) as a receptor for LPS induced cytokine production by TLR4 bearing cells. The antibody was shown to precipitate TLR4 (100kD).

Purification: Purified

Immunogène: Human TLR4.

Isotype: IgG2a

Information d'application

Indications d'application: Approved: Flo, IHC, IHC-Fr, IP, Neut

Usage: Suitable for use in Flow Cytometry, Immunoprecipitation, and Neutralization (can be used as antagonist for TLR4, it blocks LPS-induced cytokine production). Note: Before use in biological assays, the product must be sterile-filtered and depending on the concentration to be used, dialyzed against culture medium to remove the sodium azide added.

Commentaires:

Target Species of Antibody: Human

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 0.1 % BSA, 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeat freeze-thaw cycles.

Stock: 4 °C,-20 °C

Stockage commentaire: Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.

Détails sur TLR4

Antigène: TLR4 (Toll-Like Receptor 4 (TLR4))

Autre désignation: TLR4

Sujet: Name/Gene ID: TLR4
Family: Toll-like Receptor

Synonyms: TLR4, CD284, CD284 antigen, Homolog of Drosophila toll, TLR-4, TOLL, ARMD10, Toll-like receptor 4, HToll

ID gène: 7099

UniProt: O00206

Pathways: Signalisation TLR, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades, Inflammasome, S100 Proteins