TLR4 anticorps
Aperçu rapide pour TLR4 anticorps (ABIN198156)
Antigène
Voir toutes TLR4 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Specificité
- Reacts preferentially, especially in flow cytometry, with mouse TLR4 that is associated with MD-2. Recognizes the mouse TLR4/MD-2 complex and is not useful for detection of TLR4 alone.
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Purification
- Purified
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Immunogène
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Type of Immunogen: Native protein -
Isotype
- IgG2a
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Indications d'application
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Approved: Flo (1:10), IP
Usage: Can be used for Flow Cytometry and Immunoprecipitation. The antibody recognizes the mouse TLR4/MD-2 complex and is not useful for detection of TLR4 alone. Furthermore the antibody can be used as antagonist for TLR4, it blocks LPS-induced cytokine production. Flow Cytometry: 1:10. Before use in biological assays, the product must be filter sterilized and depending on the concentration to be used dialyzed against culture medium to remove the sodium azide added. Please inquire for availability of azide free solutions. -
Commentaires
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Target Species of Antibody: Mouse
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- PBS, 0.02 % sodium azide, 0.1 % BSA.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
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Short term: 4°C
Long term: Add glycerol (40-50%) -20°C.
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- TLR4 (Toll-Like Receptor 4 (TLR4))
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Autre désignation
- TLR4
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Sujet
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Name/Gene ID: TLR4
Family: Toll-like Receptor
Synonyms: TLR4, CD284, CD284 antigen, Homolog of Drosophila toll, TLR-4, TOLL, ARMD10, Toll-like receptor 4, HToll -
ID gène
- 7099
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UniProt
- O00206
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Pathways
- Signalisation TLR, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades, Inflammasome, S100 Proteins
Antigène
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