RBP4 anticorps

N° du produit ABIN1991021

Détail du produit anti-RBP4 anticorps

Antigène: RBP4 (Retinol Binding Protein 4, Plasma (RBP4))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp RBP4 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Specificité: Specific for native and denatured forms

Réactivité croisée: Humain, Souris

Purification: Protein G purified

Immunogène: Recombinant Human Retinol-binding protein 4 protein

Clone: 6A1C2

Isotype: IgG1, IgG1 kappa

Information d'application

Indications d'application: Recommended dilution:WB:1:500-1:5000,IHC:1:50-1:500,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin^TM: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur RBP4

Antigène: RBP4 (Retinol Binding Protein 4, Plasma (RBP4))

Autre désignation: RBP4 (RBP4 Produits)

Synonymes: anticorps RDCCAS, anticorps RBP, anticorps RNBP, anticorps rbp4, anticorps MGC54038, anticorps srbp, anticorps PRBP, anticorps RBPA, anticorps Rbp-4, anticorps fb23c12, anticorps rbp, anticorps wu:fb23c12, anticorps wu:fb58d04, anticorps wu:fb72b04, anticorps zgc:86911, anticorps retinol binding protein 4, anticorps renin binding protein, anticorps retinol binding protein 4 S homeolog, anticorps retinol binding protein 4 A, plasma, anticorps retinol binding protein 4, plasma, anticorps retinol binding protein 4 L homeolog, anticorps RBP4, anticorps RENBP, anticorps rbp4.S, anticorps rbp4, anticorps Rbp4, anticorps RBP4A, anticorps rbp4.L

Sujet:

Background: Retinol (Vitamin A) is transported in the blood bound to its carrier protein, retinol-binding protein (RBP), also designated plasma retinol-binding protein (PRBP) or RBP4. A member of the lipocalin family, RBP conveys retinol from stores in the liver to peripheral tissues. In plasma, RBP binds transthyretin (TTR, formerly called prealbumin) to prevent glomerular filtration of low molecular weight RBP in the kidneys. The stability of this complex holds diagnostic importance because the molar ratio of RBP:TTR provides an indirect way to indicate marginal vitamin A deficiency. Vitamin A deficiency blocks the secretion of RBP resulting in defective delivery and supply to epidermal cells. Originally identified solely as a transporter protein, recent studies correlating increased levels of RBP expression in adipose tissue with insulin resistance have generated research into the possible roles the protein may play in the pathogenesis of type 2 diabetes and obesity.

Aliases: Plasma retinol-binding protein, PRBP, RBP, RBP4, PRO2222

UniProt: P02753

Pathways: Regulatory RNA Pathways, Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis, Production of Molecular Mediator of Immune Response