p21 anticorps
Aperçu rapide pour p21 anticorps (ABIN206537)
Antigène
Voir toutes p21 (CDKN1A) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Specificité
- Recognizes the human cyclin-dependent kinase inhibitor p21/WAF1, which is an important cell cycle regulatory protein, also known as CIP1. The p21 protein inhibits cell cycle progression at both the G1 and G2 checkpoints. The expression of p21 is inducible by a wide range of stress stimuli. Detects a band of approximately 21kD in MCF-7 cell lysates following UV radiation.
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Purification
- Ammonium sulfate precipitation
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Immunogène
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Human p21 protein.
Type of Immunogen: Purified protein -
Isotype
- IgG1
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Indications d'application
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Approved: IP, WB (1:100 - 1:1000)
Usage: Immunohistology: This product does require antigen retrieval using heat treatment prior to staining of paraffin sections. Sodium citrate buffer pH 6.0 is recommended for this purpose. -
Commentaires
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Target Species of Antibody: Human
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- PBS, pH 7.4, 0.09 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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- p21 (CDKN1A) (Cyclin-Dependent Kinase Inhibitor 1A (p21, Cip1) (CDKN1A))
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Autre désignation
- CDKN1A / WAF1 / p21
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Sujet
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Name/Gene ID: CDKN1A
Synonyms: CDKN1A, CDKN1, CIP1, CDK-interacting protein 1, DNA synthesis inhibitor, p21CIP1, MDA6, PIC1, SDI1, WAF1, CAP20, CDK-interaction protein 1, MDA-6, p21 -
ID gène
- 1026
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UniProt
- P38936
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Pathways
- Signalisation p53, Signalisation PI3K-Akt, Cycle Cellulaire, AMPK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Mitotic G1-G1/S Phases, DNA Replication, Hepatitis C, Synthesis of DNA, Autophagy
Antigène
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